Table 2.

Survival times of RG2 glioma bearing rats following CED of N5–2OH with or without i.v. BPA

Group*	Number of animals	Survival time, d†			% Increased life span‡
		Mean ± SE	Median		Mean	Median
CED of N5–2OH + i.v. BPA	10	52.9 ± 8.9	52.5	42–71	122	119
CED of N5–2OH	10	45.6 ± 7.2	45	36–61	92	88
i.v. BPA	8	35.9 ± 3.3	35.5	32–41	51	48
Irradiated controls	8	28.1 ± 1.8	28	26–31	18	17
Untreated controls	10	23.8 ± 2.3	24	20–27	—	—

*N5–2OH and BPA were administered as described in a footnote in Table 1.

^†Mean and median survival times were determined for each group of 8–10 rats.

^‡Percent increased life span (% ILS) was defined relative to mean and median survival times of untreated controls.