Fig. 5.

EtOH consumption is higher in β4 KO. (A) EtOH consumption of WT (black squares) and β4 KO mice (white squares) using a restricted access single bottle self-administration assay. Measurements were taken every day for four days for 2 h after lights were turned off. (B) Average daily EtOH intake in male and female WT and KO mice. (C and D) Water, sucrose, and quinine intake of WT (black squares and circles) and KO (white squares and circles) mice, respectively (n = 5–8 per genotype). No significant difference was observed in either condition. One Way ANOVA, Tukey posthoc, * P < 0.05, ** P < 0.01, *** P < 0.001.