TABLE 5.

Identity and frequencies of haplotypes for apoH amino acid substitutions and results of HBAT association analysis

											Association Results European Americans					Association Results Mexican Americans
	Amino Acid Substitutions							GENOA Frequencies			HCT			RCT		HCT	DCT		RCT
Protein Isoforms	Ser88Asn	Ile122Thr	Arg135His	Ala141Asp	Val247Leu	Cys306Gly	Trp316Ser	EA	AA	MA	TC	LDLC	ApoB	HDL	ApoA1	TC	TG	ApoE	HDL
H*1	N	I	R	A	L	C	W	0.051		0.025	ns	ns	ns	0.024	0.026	ns	ns	ns	ns
H*2	S	I	R	A	L	C	W	0.571	0.385	0.431	ns	ns	ns	ns	ns	ns	ns	ns	ns
	S	I	R	A	V	C	W	0.255	0.558	0.431	ns	ns	ns	ns	ns	ns	ns	ns	ns
	S	I	R	A	L	G	W	0.033		0.056	ns	ns	ns	ns	ns	0.018	0.002	0.0007	ns
H*3	S	T	H	A	L	C	W	0.015	0.031	0.010	0.010	0.033	0.009	ns	ns	ns	ns	ns	ns
H*3W	S	T	H	A	L	C	S	0.069		0.042	ns	ns	ns	ns	0.015	0.014	ns	ns	0.013
H*3B	S	T	H	N	L	C	W				na	na	na	na	na	na	na	na	na

RCT, reverse cholesterol transport. ns, not significant (P > 0.05); number of informative families <10.