Table 3. Solvated cavities in interface and their hydrogen-bonding pattern.
| Interface Type | ||
| Inter_H | Inter_C | |
| No. of solvated cavities | 361 | 215 |
| No. of water molecules | 896 | 425 |
| No. with HB (both)a | 334 | 217 |
| HB (single) | 471 | 185 |
| HB (none) | 91 | 23 |
The labels, given in the first column, indicate the number of water molecules that are hydrogen bonded to both the subunits across the interface, or to just one of them, or none at all.
a
Considering the contacts within 4.0 Å (not necessarily hydrogen bonds) from both the sides, the numbers are 645 and 358, respectively.