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Vascular Regulation of the TF ELK3 and MEF2A by Estrogen Requires Vascular ERα
Wild-type, ERα-KO, and ERβ-KO aortas were treated ex vivo with estrogen or vehicle for 4 h. qRT-PCR was used to quantify ELK3 (A) or MEF2A (B) expression normalized to β2-microglobulin expression. Bars indicate mRNA fold change compared with the average of the vehicle control: gray, vehicle; black, estrogen treated. *, P < 0.05 vs. vehicle; #, P < 0.05 vs. estrogen-treated wild type.
