Table 1.
Study population characteristics
| No. | Sample 1 | No. | Sample 2 | P value | |
|---|---|---|---|---|---|
| Male/female | 28/50 | 14/72 | |||
| Ethnicity (white/Black/Hispanic) | 54/24/0 | 72/13/1 | |||
| Age (yr) | 78 | 42.3 (8.8) | 86 | 42.7 (10.0) | NS |
| BMI (kg/m2) | 78 | 28.7 (5.6) | 86 | 31.0 (4.8) | 0.005 |
| PFAT (%) | 77 | 32.9 (10.3) | 86 | 38.4 (7.6) | 0.0002 |
| Waist circ (cm) | 77 | 95.2 (13.5) | 74 | 96.4 (14.4) | NS |
| Waist to hip ratio | 77 | 0.879 (0.072) | 74 | 0.886 (0.085) | NS |
| Systolic BP (mm Hg) | 78 | 124.2 (13.2) | 75 | 116.2 (21.4) | 0.006 |
| Diastolic BP (mm Hg) | 78 | 77 (10) | 75 | 75.7 (14.4) | NS |
| Total cholesterol (mmol/liter) | 78 | 4.58 (0.93) | 75 | 4.91 (1.05) | 0.05 |
| HDL cholesterol (mmol/liter) | 78 | 1.38 (0.83, 2.29) | 75 | 1.31 (0.76, 2.28) | NS |
| LDL cholesterol (mmol/liter) | 78 | 2.49 (1.37, 4.56) | 69 | 2.69 (1.45, 5.00) | 0.11 |
| Triglycerides | 78 | 1.08 (0.39, 3.00) | 75 | 1.32 (0.45, 3.87) | 0.02 |
| SI [×10−4 min−1 (μU/ml)−1] | 77 | 3.16 (1.08, 9.26) | 83 | 2.40 (0.69, 8.39) | 0.004 |
| AIRg (mg-min/dl) | 77 | 370 (70.0, 1960) | 83 | 328 (63, 1697) | NS |
| DI | 77 | 1169 (236, 5805) | 83 | 768 (160, 3690) | 0.001 |
The traits shared between the primary study population (sample 1) and replication population of previously examined individuals ascertained under other studies (sample 2) are shown. Skewed variables are shown as mean (95% CIs); normal variables are mean (sd). P values are from a two-tailed t test comparing the two populations. Note that the numbers of subjects used in subsequent tables and figures removed some individuals who were not of Caucasian or African-American ancestry, were studied under a different protocol, or could not be modeled for FSIGT data. For conversion to mass units (mg/dl) divide cholesterol by 0.0259 and triglycerides by 0.0113. BP, Blood pressure; HDL, high-density lipoprotein; LDL, low-density lipoprotein; NS, not significant; PFAT, percent fat from DXA; Waist circ, waist circumference.