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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: J Neurochem. 2008 Sep 11;107(5):1196–1205. doi: 10.1111/j.1471-4159.2008.05664.x

Figure 6.

Figure 6

Effect of NBO on MMP-9 induction in ischemic cerebral microvessels after 90-min MCAO with 22.5-hr reperfusion. Cerebral microvessel lysates (50 μg) were analyzed for MMP-9 expression with gelatin zymography. A) Representative gelatin zymogram showing MMP-9 expression in the nonischemic (Non-I) and ischemic (I) hemispheric cerebral microvessels. STD is a mixture of standard MMP-2 and MMP-9. B) The relative band intensity of MMP-9 was quantified. A significant increase was observed for MMP-9 expression in the ischemic hemispheric microvessels in both normoxic and NBO-treated rats (*P < 0.05 versus nonischemic hemispheric microvessels). NBO significantly reduced MMP-9 expression in the ischemic hemispheric microvessels (#P < 0.05 versus vehicle-treated rats). Data are expressed as mean ±SEM, n = 6 in each group.