Figure 1.

Workflow of gene expression module-based similarity search. Workflow of expression function pattern similarity search: (A) A query profile is uploaded and GOMs significantly affected are found using hypergeometric test; (B) for each GOM found in the first step, expression pattern comparison is performed between the query and every reference instance to calculate for each GOM a S score and a P-value. Instances whose P-value is above the threshold (default is 0.05) are filtered out. Instances are arranged in descending order according to the number of matched (or reverse-matched) GOMs; (C) results are returned in both graphic and textual forms.