Table 1.
Top 10 reference instances found for profiles of VPA-treated cells
| cMap ID | Molecule | Dose | Cell line | GO counts |
|---|---|---|---|---|
| 1072 | Trichostatin A | 1 µM | MCF7 | 21(20+, 1−) |
| 410 | VPA [INN] | 10 mM | HL60 | 20(20+, 0−) |
| 1000 | Vorinostat | 10 µM | MCF7 | 20(20+, 0−) |
| 1050 | Trichostatin A | 100 nM | MCF7 | 20(20+, 0−) |
| 909 | HC toxin | 100 nM | MCF7 | 19(19+, 0−) |
| 989 | VPA [INN] | 1 mM | MCF7 | 19(19+, 0−) |
| 332 | Trichostatin A | 100 nM | MCF7 | 18(18+, 0−) |
| 1112 | Trichostatin A | 100 nM | MCF7 | 17(17+, 0−) |
| 866 | Ikarugamycin | 2 µM | MCF7 | 17(17+, 0−) |
| 409 | VPA [INN] | 1 mM | HL60 | 16(16+, 0−) |
The top 10 instances sharing the largest number of significantly affected GOMs with VPA-treated cells are listed here. For detailed parameter settings: BP is chosen as GO mode, the permutation time is set to be 1000, and the P-value for cutting off insignificantly matched or reverse-matched GO modules is 0.05. ‘plus’ indicates the number of GO terms positively correlated; ‘minus’ indicates the number of GO terms negatively correlated.