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. 2008 Oct 14;36(20):6459–6471. doi: 10.1093/nar/gkn657

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© 2008 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Hydrogen-bonding interactions between (A) a G:C pair, O⁶-meG and (B) cytosine, (C) uridine and (D) adenine, respectively (see text). (A) G:C pair; G(O⁶):C(N⁴), G(N1):C(N3), and G(N²): C(O²), (B) anti,proximal O⁶-meG:C pair; O⁶-meG(O⁶):C(N⁴) and O⁶-meG(N²): C(O²), (C) anti,proximal O⁶-meG:U pair; O⁶-meG(N1): U(N3) and O⁶-meG(N²):U(O²) and (D) syn, distal O⁶-meG:A pair; O⁶-meG(O⁶): A(N⁶). Hydrogen bonds involving potential protonation sites, O⁶-meG(N1):C(N3⁺) and O⁶-meG(N7):A(N1⁺) are shown in pink. The methyl group carbon is colored in green. Color code is the same as in Figure 3. Details of the potential hydrogen-bonding partners are described in Supplementary Table S2.