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RNase H activity of wild-type HIV-1 RT on substrates containing triple methylphosphonate substitutions. Lane denominations are: lane a, −10/−11/−12; lane b, −11/−12/−13; lane c, −12/−13/−14; lane d, −13/−14/−15; lane e, −14/−15/−16; lane f, −15/−16/−17; lane g, −16/−17/−18; lane h, −17/−18/−19 and lane i, −18/−19/−20.
