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. 2008 Oct 4;36(20):6363–6371. doi: 10.1093/nar/gkn678

Figure 6.

Figure 6

RNA-dependent DNA polymerase activity of HIV-1 RT on dual-substituted RNA/DNA hybrids (A), Lane C, wild-type substrate; lane a, −10/−11; lane b, −11/−12; lane c, −12/−13; lane d, −13/−14; lane e, −14/−15; lane f, −15/−16; lane g, −16/−17; lane h, −17/−18; lane i, −18/−19 and lane j, −19/−20. (B), RNA-dependent DNA synthesis with triply-substituted RNA/DNA hybrids. Lane C, wild-type substrate; lane a, −10/−11/−12; lane b, −11/−12/−13; lane c, −12/−13/−14; lane d, −13/−14/−15; lane e, −14/−15/−16; lane f, −15/−16/−17; lane g, −16/−17/−18; lane h, −17/−18/−19 and lane i, −18/−19/−20.