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Plasma cytokines. Rats treated with vehicle or AT1 antagonist for 3 d received an ip injection of sterile saline or LPS on d 3. The animals were killed 3 h later. Values are mean ± sem for groups of seven to nine animals measured individually. **, P < 0.01 as compared with the candesartan-LPS treated groups; one-way ANOVA and post hoc Tukey’s test. ND, Nondetectable.
