Table 4.
Significantly regulated genes related to mitochondrial function and metabolism
| Gene ID | Gene name | Fold change |
|---|---|---|
| 18746 | Pyruvate kinase, muscle | 1.64 |
| 18618 | Phosphatidylethanolamine n-methyltransferase | 1.43 |
| 67681 | Mitochondrial ribosomal protein L18 | 1.43 |
| 67582 | Solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26 | 1.42 |
| 12856 | Cytochrome c oxidase, subunit XVII assembly protein homolog (yeast) | 1.36 |
| 20655 | Superoxide dismutase 1, soluble | 1.35 |
| 14467 | Glioblastoma amplified sequence | 1.34 |
| 22262 | Urate oxidase | 1.33 |
| 28030 | G elongation factor, mitochondrial 1 | 1.32 |
| 68375 | NADH dehydrogenase (ubiquinone) 1 α-subcomplex, 8 | 1.29 |
| 66988 | Leucine aminopeptidase 3 | 1.29 |
| 13171 | Dihydrolipoamide branched chain transacylase E2 | 1.28 |
| 50776 | Polymerase (DNA directed), γ-2, accessory subunit | 1.26 |
| 20916 | Succinate-coenzyme A ligase, ADP-forming, β subunit | 1.25 |
| 15494 | Hydroxy-δ-5-steroid dehydrogenase, 3 β- and steroid δ-isomerase 3 | 1.25 |
| 15512 | Heat shock protein 2 | 1.25 |
| 12039 | Branched chain ketoacid dehydrogenase E1, α polypeptide | 1.24 |
| 104910 | Expressed sequence AI132487 | 1.24 |
| 57423 | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f, isoform 2 | 1.23 |
| 18975 | Polymerase (DNA directed), γ | 1.20 |
| 50529 | Mitochondrial ribosomal protein S7 | 1.20 |
| 69955 | Phenylalanine-tRNA synthetase 2 (mitochondrial) | 1.18 |
| 53895 | Caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (Escherichia coli) | 1.16 |
| 269951 | Isocitrate dehydrogenase 2 (NADP+), mitochondrial | 1.15 |
| 15488 | Hydroxysteroid (17-β) dehydrogenase 4 | 0.87 |
| 29876 | Chloride intracellular channel 4 (mitochondrial) | 0.85 |
| 71701 | Polyribonucleotide nucleotidyltransferase 1 | 0.84 |
| 30057 | Translocase of inner mitochondrial membrane 8 homolog b (yeast) | 0.83 |
| 28295 | DNA segment, Chr 10, Johns Hopkins University 81 expressed | 0.83 |
| 14194 | Fumarate hydratase 1 | 0.83 |
| 66841 | Electron transferring flavoprotein, dehydrogenase | 0.81 |
| 68463 | Mitochondrial ribosomal protein L14 | 0.81 |
| 16973 | Low-density lipoprotein receptor-related protein 5 | 0.80 |
| 53333 | Translocase of outer mitochondrial membrane 40 homolog (yeast) | 0.80 |
| 67270 | DNA segment, Chr 10, ERATO Doi 322, expressed | 0.53 |
Gene identifier (ID) is the EntrezGene accession number that uniquely identifies the gene. Fold change is the ratio of the mean expression of the indicated gene in diabetic mice to control mice. Chr, Chromosome; NADH, reduced nicotinamide adenine dinucleotide; NADP, nicotinamide adenine dinucleotide phosphate.