Table 2. IC50 values for FAK inhibitors.
Inhibitor | IC50 (nM) |
TAE226 | 6.24±0.51 |
TAF089 | 7.70±1.36 |
AZW592 | 17.76±1.21 |
IC50 values were calculated by fitting the Hill slope model to inhibition curves determined at a concentration of 10 nM purified FAK kinase and 1 mM ATP.