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. 2008 Nov 18;3(11):e3752. doi: 10.1371/journal.pone.0003752

Figure 6. Notch pathway modulation on BM-PC regulates their angiogenic and their wound healing properties in vivo.

Figure 6

A. Quantification of wound area in Balb-C mice injected with PBS, control BM-PC, GSI BM-PC or sDll4 BM-PC. Area at each time point is expressed relatively to the area measured immediately after wounding. B. Representative images of the wounds at days 0, 4, 8 and 12. C. Representative histological images of wounds collected at day 14 after wounding. Hematoxilin and Eosin staining. Scale bar represented. D. Quantification of vessel basement membrane immunostaining for laminin in the wound tissue of PBS, C-BM-PC or GSI BM-PC injected mice at day 14 post-wounding. E. Representative image of laminin and VWF immunostaining (* identifies VWF positive staining) in wounds of PBS, C-BM-PC or GSI BM-PC injected mice. Scale bar represented. *P<0.05 Each experiment was performed in triplicate and the mean presented (n = 3).