Table 1. Description of diagnostic groups*.
Total | High risk | Other | Comparisons high risk vs other | |
---|---|---|---|---|
No. of subjects | 681 | 27 | 654 | |
Age at PSA, years | ||||
Median (range) | 68.8 (42.3, 95.3) | 77.1 (56.8, 88.1) | 68.4 (42.3, 95.3) | |
Mean (SD) | 67.8 (11.7) | 75.6 (7.8) | 67.5 (11.7) | p < 0.001 |
Time from PSA test or cancer diagnosis to death or censoring† | ||||
Median (range) | 5.9 (0, 34.6) | 7.4 (2, 24.6) | 5.9 (0, 34.6) | p = 0.447 |
Mean (SD) | 7.1 (5.01) | 7.8 (5) | 7.1 (5) | |
PSA (ng/ml) at index visit | ||||
Median (range) | 1.6 (0.1, 351.9) | 16.5 (0.5, 351.9) | 1.5 (0.1, 18.6) | p = 0.015 |
Mean (SD) | 3.9 (16) | 38.5 (72.1) | 2.5 (2.8) |
Abbreviations: PSA, prostate-specific antigen; SD, standard deviation; pCA, prostate cancer.
Subjects consisted of 681 participants in the Baltimore Longitudinal Study of Aging with or without high-risk pCA (see “Methods” for description of diagnostic groups). Comparisons were by pooled t tests in the case of equal variances and Cochran t tests in the case of unequal variances; all statistical tests were two-sided.
Time from last PSA test to censoring for those without pCA or time from diagnosis of pCA to death or censoring for those with pCA.