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Effect of kallikrein on Akt and GSK-3β activation and vascular endothelial growth factor and vascular endothelial growth factor receptor-2 expression. (A) Western blots for Akt and GSK-3β. (B) GSK-3β activity. (C) Vascular endothelial growth factor (VEGF) and (D) vascular endothelial growth factor receptor-2 (VEGFR-2) mRNA levels determined by real-time polymerase chain reaction. Values are expressed as mean ± SEM [n = 6–7, *P < 0.05 vs. other myocardial infarction (MI) groups].
