Table 1.
Demographics, baseline characteristics and final diagnosis of MRSA patients
| Daptomycin (n = 45) | Vancomycin/gentamicin (n = 43) | |
|---|---|---|
| Age (years), median (range) | 57 (22–86) | 54 (25–91) |
| Gender (male), n (%) | 23 (51) | 25 (58) |
| Race, n (%) | ||
| black | 10 (22) | 9 (21) |
| Caucasian | 31 (69) | 29 (67) |
| Hispanic | 3 (7) | 2 (5) |
| other | 1 (2) | 3 (7) |
| Weight (kg), median (range) | 70.5 (52.0–119.4) | 71.5 (49.9–119.9) |
| BMI (kg/m2), median (range) | 26.5 (18.6–49.6) | 25.4 (18.9–44.0) |
| Creatinine clearance (mL/min), median (range) | 77.6 (29.4–200.8) | 76.3 (17.9–171.0) |
| Underlying conditions, n (%) | ||
| injection drug use | 12 (27) | 11 (26) |
| diabetes mellitus | 17 (38) | 18 (42) |
| septic pulmonary emboli | 4 (9) | 5 (12) |
| HIV infection | 2 (4) | 0 |
| history of endocarditis | 3 (7) | 3 (7) |
| underlying valvular heart disease | 9 (20) | 6 (14) |
| presence of foreign material | ||
| intravascular | 5 (11) | 9 (21) |
| extravascular | 14 (31) | 14 (33) |
| SIRS | 35 (78) | 33 (77) |
| Final diagnosis, n (%)a | ||
| uncomplicated bacteraemia | 10 (22) | 11 (26) |
| complicated bacteraemia | 22 (49) | 22 (51) |
| right-sided endocarditis | 8 (18) | 6 (14) |
| left-sided endocarditis | 5 (11) | 4 (9) |
BMI, body mass index; HIV, human immunodeficiency virus; SIRS, systemic inflammatory response syndrome.
aAs determined by the adjudication committee.