In situ hybridisations on mouse retinal cryosections using DIG-labelled riboprobes. Results for antisetise and sense probes for (A) IMPDH1, (B) IMPDH2 and (C) HPRT are shown. The IMPDH2 in situs are performed on CD1 mouse retinas which lack pigment in the RPE while the IMPDH1 and HPRT in situs are performed on wild type pigmented retinas. (RPE) retinal pigment epithelium, (OS) outer segments, (ONL) outer nuclear layer, (OPL) outer plexiform layer, (INL) inner nuclear layer, (IPL) inner plexiform layer, (GCL) ganglion cell layer. 200X Magnification.