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. 2008 Oct 14;4:223. doi: 10.1038/msb.2008.59

Figure 4.

Figure 4

Two alternative models that might account for the observed coordination between transcription and degradation. Our results suggest coordination between changes in transcription to changes in mRNA degradation; this might be achieved by at least two alternative models: The first (i) suggests direct coupling between transcription and degradation meaning that mRNA degradation is directly affected by the rates of production. According to a possible alternative model (ii), the sensor of the stress activates a transcriptional response and, independently of that, it also induces a change in stability of the transcripts.