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. Author manuscript; available in PMC: 2009 Jun 11.
Published in final edited form as: FEBS Lett. 2008 May 15;582(13):1835–1839. doi: 10.1016/j.febslet.2008.05.003

Figure 1.

Figure 1

(A) The sequence and secondary structure of Macugen. 2f and 2m indicate 2′-fluoro and 2′-O-methyl modifications. Temperature-dependent imino proton spectra of (B) free Macugen, (C) the HBD-Macugen complex and (D) the VEGF-Macugen complex.