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The structures of the modified nucleosides a) N4, 2′-O-dimethylcytidine (m4Cm), b) 5-methylcytidine (m5C), c) 3-methyluridine (m3U), d) cytidine (C), e) 2′-O-methylcytidine (Cm), and f) N4, methylcytidine (m4C) are shown.