Table 1.
Drug | Serum (μg/ml) | Ilium (μg/g) | Sclerotic wall of vertebrae (μg/g) | Subnormal bone (μg/g) | Foci inside sclerotic wall (μg/g) |
---|---|---|---|---|---|
RFP | 8.94 ± 2.15** | 4.87 ± 1.65 | 0.47 ± 0.11** | 4.32 ± 1.59 | Undetected |
INH | 5.48 ± 2.73** | 2.23 ± 0.78 | 0.057 ± 0.011** | 2.14 ± 0.74 | Undetected |
PZA | 31.54 ± 6.78** | 7.61 ± 2.62 | 0.82 ± 0.26** | 7.58 ± 2.45 | Undetected |
Compared with ilium in same drug group (except focus inside sclerotic wall), *P < 0.05; **P < 0.01