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. 2008 Sep 17;17(11):1423–1430. doi: 10.1007/s00586-008-0783-x

Table 4.

Effects of paracetamol on pain and disability outcomes (presented on 0–10 scale)

Outcome Comparison Effect size (95% CI) Paracetamol Comparison
Week Mean SD N Mean SD N
Pain
 Stein [17] 1 Amitriptyline 0.0 (−1.3 to 1.3) 4.7a 2.2c 19 4.7a 1.8c 20
2 Amitriptyline 1.1 (−0.1 to 2.3) 3.6a 1.8b 19 2.5a 1.9b 20
3 Amitriptyline 1.2 (−0.1 to 2.5) 3.5a 2.0b 19 2.3a 2.1b 20
4 Amitriptyline 1.5 (0.1 to 2.9) 3.4a 2.3b 19 1.9a 2.3b 20
5 Amitriptyline 1.2 (0 to 2.4) 3.0 2.5 19 1.8 1.0 20
 Hackett [8] 1 Electro-acupt 0.0 (−1.2 to 1.3) 2.3 2.0c 20 2.3 2.0c 20
2 Electro-acupt 0.4 (−0.9 to 1.6) 2.2 2.0c 20 1.8 2.0c 20
6 Electro-acupt 1.0 (−0.2 to 2.3) 1.4 2.0c 20 0.3 2.0c 20
Disability
 Hackett [8] 1 Electro-acupt −0.2 (n/c) 2.5 n/c 20 2.7 n/c 20
2 Electro-acupt −0.1 (n/c) 1.7 n/c 20 1.8 n/c 20
6 Electro-acupt 1.4 (n/c) 1.6 n/c 20 0.2 n/c 20

Effect size difference of means (negative means paracetamol gives greater reduction), SD standard deviation, N number in group, 95% CI 95% confidence interval, Electro-acupt electroacupuncture, n/c not able to be calculated

aEstimated value from a graph

bCalculated SD from other data

cEstimated SD