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The effect of purinergic compounds on [Ca2+]i in a mouse single islet in culture and beta-TC6 cells. The following compounds were tested: ATP (100 μM), 2-MeSADP (100 μM), ADP (100 μM), and UDP (200 μM). The effect of the nucleotides on [Ca2+]i is shown as % of the peak response induced by ATP (100 μM) in the mouse single islet in culture (a) and beta-TC6 cells (b) in the presence of 5.5 mM glucose. Each bar represents the mean ± SE (n = 7–15 in a and n = 24–54 in b)
