Table 3.

Longitudinal mfERG Changes Depending on Fundus Alterations

Fundus: Abnormal mfERGs*	Drusen Progression, %	Drusen Unchanged, %	Drusen Regression With RPE Changes, %
Central 10° retinal eccentricity
P1-N1 response density	1.8–11.4†	3.9–21.0†	0–12.3†
N1 implicit time	4.4–8.8†	5.3–6.6	15.8–28.1
P1 implicit time	7.0–10.5	12.5–13.2	31.6–36.8
N2 implicit time	9.6-7.0	19.7-9.2†	47.4–52.6
Outside 10° retinal eccentricity
P1-N1 response density	1.2–6.2†	4.2–15.0†	0–2.0†
N1 implicit time	6.9–9.1†	8.5–11.6†	10.7–25.0†
P1 implicit time	3.8–6.7†	6.0-5.5	13.5–27.4†
N2 implicit time	5.2–6.0	8.6-4.2	14.7–27.4†

Abbreviations: mfERG, multifocal electroretinogram; RPE, retinal pigment epithelium.

^*Percentage of the mfERGs that are delayed or reduced of ≥2 SD in comparison with the normal controls.

^†Significant (adjusted P≤.001).