Table 1.

Interaction Energies Balance (kJ/mol) for Different Solute–Solvent Systems

solute type	〈Nwet〉a	${\text{E}}_{\text{HB}}^{\text{lost}}$	∊CC	Euvb
solute-I	5.8	34.8	0.1	−54.2
			0.2	−96.1
solute-II	15.2	91.2	0.1	−59.8
			0.2	−177.4
solute-III	48.5	291.0	0.1	−171.6
			0.2	−540.1

^aAverage number of intersolute water in the fully wet state.

^bSolute–solvent potential energy/2.