Table 1.
Demographic and ionizing radiation exposure variable distributions among cases and controls, US Radiologic Technologists study
| Characteristic | Cases (%)
(n = 859) |
Controls (%)
(n = 1083) |
Odds Ratio* | 95% Confidence Interval | p-trend† | |
|---|---|---|---|---|---|---|
| Ethnicity | ||||||
| Caucasian | 842 (98) | 1048 (97) | 1.0 | N/A | ||
| African American | 9 (1) | 18 (2) | 0.6 | 0.3 | 1.4 | |
| Other | 8 (1) | 17 (2) | 0.6 | 0.3 | 1.4 | |
| Year of Birth | ||||||
| ≤ 1925 | 120 (14) | 138 (13) | 1.0 | 0.7 | ||
| 1926 – 1935 | 195 (23) | 249 (23) | 1.1 | 0.9 | 1.5 | |
| 1936 – 1945 | 292 (34) | 382 (35) | 1.0 | 0.8 | 1.3 | |
| >1945 | 252 (29) | 314 (29) | 1.0 | 0.8 | 1.3 | |
| Occupational Ionizing Radiation Breast Dose (Gy)§ | ||||||
| 0 to 0.05 | 687 (80) | 894 (83) | 1.0 | 0.2 | ||
| >0.05 to 0.1 | 90 (10) | 100 (9) | 1.2 | 0.9 | 1.7 | |
| >0.1 to 0.2 | 63 (7) | 76 (7) | 1.1 | 0.7 | 1.6 | |
| >0.2 | 19 (2) | 13 (1) | 1.9 | 0.9 | 4.0 | |
| Personal Diagnostic x-ray Breast Dose Score§ | ||||||
| 0 to 0.05 | 686 (80) | 908 (84) | 1.0 | 0.06 | ||
| >0.05 to 0.1 | 106 (12) | 104 (10) | 1.3 | 1.0 | 1.8 | |
| >0.1 to 0.2 | 46 (5) | 51 (5) | 1.2 | 0.8 | 1.8 | |
| >0.2 | 21 (2) | 20 (2) | 1.4 | 0.7 | 2.6 | |
| Radionuclide Procedures | ||||||
| Never | 721 (84) | 937 (87) | 1.0 | NA | ||
| Ever | 65 (8) | 71 (7) | 1.2 | 0.8 | 1.7 | |
| Unknown | 73 (9) | 75 (7) | N/A | |||
| Radiation Therapy | ||||||
| Never | 803 (93) | 1021 (94) | 1.0 | NA | ||
| Ever | 24 (3) | 14 (1) | 2.1 | 1.0 | 4.0 | |
| Unknown | 32 (4) | 48 (4) | N/A | |||
All Odds Ratios Adjusted for Year of Birth categories; Occupational Dose and Personal Diagnostic Dose Score analyses mutually adjusted (categorically); Radionuclide Procedure analysis adjusted for Occupational Dose categories, Personal Diagnostic Dose Score categories and Radiation Therapy categories; Radiation Therapy analysis adjusted for Occupational Dose categories, Personal Diagnostic Dose Score categories and Radionuclide Procedures categories
Trend test with categories of interest modeled as continuous variables in logistic regression analyses; adjusted for applicable covariates as indicated above
EOR/Gy (Excess Odds Ratio) for Occupational Dose is 3.0 (p = 0.05); EOR/dose score for personal diagnostic x-ray breast dose score is 1.3 (p = 0.2); OR = 1 + EOR*(dose)