Table 4.

Odds ratios and 95% confidence intervals for the effect of exposures postulated to influence host/tumour interactions on melanoma relapse

	Non-relapsers N (%)	Relapsers N (%)	Odds ratio (95% CI)	p-Valueb
Polio immunisationa
Never/>5 years ago	105 (90.5)	76 (87.4)	1.0	0.5
In the last 5 years	11 (9.5)	11 (12.6)	1.4 (0.6, 3.4)
Flu immunisationa
Never/>5 years ago	69 (53.9)	48 (60.8)	1.0	0.3
In the last 5 years	59 (46.1)	31 (39.2)	0.8 (0.4, 1.3)
Tetanus immunisationa
Never/>5 years ago	92 (73.6)	76 (83.5)	1.0	0.1
In the last 5 years	33 (26.4)	15 (16.5)	0.6 (0.3, 1.1)
Yellow fever immunisationa
Never	112 (87.5)	84 (87.5)	1.0	1.0
Ever	16 (12.5)	12 (12.5)	1.0 (0.4, 2.2)
Any immunisation in the last 5 yearsa,c
No	29 (25.0)	26 (33.8)	1.0	0.2
Yes	87 (75.0)	51 (66.2)	0.7 (0.3, 1.2)
Use of any drugs after diagnosis
No	85 (57.8)	87 (66.4)	1.0	0.1
Yes	62 (42.2)	44 (33.6)	0.7 (0.4, 1.1)
Use of statins
No	144 (98.0)	123 (93.9)	1.0	0.1
Yes	3 (2.0)	8 (6.1)	3.1 (0.8, 12.0)
Any oestrogen
No	141 (95.9)	126 (96.2)	1.0	0.9
Yes	6 (4.1)	5 (3.8)	0.9 (0.3, 3.1)
Wound healing problems after primary
No	115 (80.4)	99 (82.5)	1.0	0.7
Yes	28 (19.6)	21 (17.5)	0.9 (0.5, 1.6)
Skin graft for primary
No	77 (60.2)	68 (58.1)	1.0	0.7
Yes	51 (39.8)	49 (41.9)	1.1 (0.7, 1.8)
Antibiotics after surgery
No	109 (76.2)	108 (90.0)	1.0	0.003
Yes	34 (23.8)	12 (10.0)	0.4 (0.2, 0.7)

Odds ratios and 95% confidence intervals from unadjusted analysis.

^aAnalysis restricted to the 104 relapsers who were interviewed within two years of relapse.

^bLikelihood ratio chi-squared p-value.

^cBased on immunisations against polio, flu, pneumonia, hepatitis A, hepatitis B, bacilli Calmette-Guerin (BCG), meningitis and tetanus.