Table 3.
Summary effects of steroid hormone on ORL1 and G protein kinetics in medial preoptic area and mediobasal hypothalamus membranes
Medial preoptic area |
Mediobasal hypothalamus |
|||
---|---|---|---|---|
EB | EB + P | EB | EB + P | |
Bmax | – | ↑ | ↑ | ↑ |
Kd | – | ↑ | ↑ | ↑ |
GproteinBmax | – | – | – | – |
GproteinKd | – | – | – | – |
Emax | – | ↑ | ↑ | ↑↑ |
CA | – | ↓ | ↓ | ↓ |
EB = 17β-Estradiol benzoate; P = progesterone. Effects of steroid hormone on ORL1 kinetics and catalytic amplification (CA): no comparable differences compared to oil-treated animals (–); one arrow (↓ or ↑) significantly different compared to oil-treated animals (p < 0.05); two arrows (↑ ↑) significantly different compared to EB Emax mediobasal hypothalamus (p < 0.05).