Table 4. Adjusted Mean LDL-c and HDL-c Levels by Menopausal Status, ARIC.

	Pre-/Perimenopausal	Postmenopausal	Difference in Means	P-value for Interaction
LDL-c, mg/dL
Apolipoprotein E
ε22/ε23	105.9 ± 1.75	116.0 ± 1.19	10.1	0.47
ε34/ε44	130.6 ± 1.25	138.4 ± 0.86	7.8
ε33	124.1 ± 0.88	132.0 ± 0.60	7.9
HDL-c, mg/dL
Cholesteryl Ester
Transfer Protein
AA	61.2 ± 0.70	60.6 ± 0.52	-0.6	0.04
AG	58.4 ± 0.42	57.6 ± 0.30	-0.8
GG	54.9 ± 0.45	55.3 ± 0.33	0.4
Hepatic Lipase
TT	59.5 ± 0.89	59.6 ± 0.65	0.1	0.80
TC	58.5 ± 0.46	58.2 ± 0.33	-0.3
CC	56.6 ± 0.39	56.2 ± 0.29	-0.4
Lipoprotein
Lipase
GG/CG	59.3 ± 0.63	59.6 ± 0.47	0.3	0.13
CC	57.2 ± 0.32	56.6 ± 0.23	-0.6

Values are mean (mg/dL) ± standard error across up to 4 ARIC visits.

Means are adjusted for visit, age, a combined center/race variable, body mass index, smoking, use of cholesterol lowering medications, and use of hormone replacement therapy.