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. 2008 Nov 12;5(6):361–365. doi: 10.7150/ijms.5.361

FIGURE 1.

FIGURE 1

Seven tiled siRNAs designed to target the region surrounding the T/C single nucleotide polymorphism (SNP) rs1800222 in the COL1A2 gene. Capital letters visualize 19 nucleotides of the antisense siRNA strand that are perfectly complementary to the T-allele of rs1800222. Each siRNA-strand had a two-nucleotide 3-prime overhang, which is visualized as non-capital letters in the antisense strands of siRNAs 1-7.