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Most common or serious hematologic and nonhematologic toxicities.
| Toxicity | Grade 2 | Grade 3 | Grade 4 | |||
|---|---|---|---|---|---|---|
| No. | % | No. | % | No. | % | |
| Hematologic | ||||||
| Neutropenia | 2 | 8 | 1 | 4 | ||
| Thrombocytopenia | 3 | 13 | 1 | 4 | ||
| Anemia | 2 | 8 | 1 | 4 | ||
| Non-hematologic | ||||||
| Nausea | 8 | 33 | ||||
| Emesis | 8 | 33 | 2 | 8 | ||
| Fatigue | 12 | 50 | 1 | 4 | ||
| Neurologic toxicity | 5 | 21 | 3 | 12 | ||
| Constipation | 10 | 42 | ||||
| Anorexia | 5 | 21 | ||||
| Edema | 3 | 13 |
