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. 2008 Aug 11;29(6):726–776. doi: 10.1210/er.2008-0004

Table 1.

Properties of VDR

Molecular mass 50 kDa (human VDR)
Kd
 1,25-(OH)2D 10−10m
 25-OHD 10−8m
Isoelectric point 6.2
Tissue concentration 0.01–1 pmol/mg protein
200–25,000 copies/cell
Structural variants
 VDR-A (f-allele) 427 Amino acids
 VDR-A (F-allele) 424 Amino acids, by alternative translation start site
 VDR-B1 477 Amino acids, by N-terminal extension
Polymorphisms
 Large number in 5′ promoter cdx-2
 N terminal Fok I
 C terminal BsmI, ApaI, TaqI, TruI, polyA microsatellite