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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: J Neurovirol. 2008 Apr;14(2):152–163. doi: 10.1080/13550280801958930

Figure 5.

Figure 5

Effect of hE16 (32 mg/kg) administered i.p. after injection of 101.8 p.f.u. of WNV into the spinal cord at the T8 vertebra of hamsters. (A) Hind limb paralysis and mortality were monitored when administered with hE16 for 2, 3, 4, or 5 days. The numbers of affected/total animals are indicated in the figure above the bars. (B) WNV RNA in the cervical, thoracic, and lumbar spinal cord of 3 hamsters treated i.p. with hE16 (32 mg/kg) and 3 hamsters treated with placebo on day 3 when assayed at 6 days after injection of WNV. (C) Alkaline phosphatase staining of WNV antigen in spinal cord at cervical, thoracic, and lumbar vertebrae from hamsters 6 days after injection of WNV. Hamsters were treated i.p. with 0.1 ml of sterile physiological saline or with 32 mg/kg of hE16 administered 3 days after viral challenge. Scale bar = 20 μm.