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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: J Hypertens. 2008 Dec;26(12):2414–2425. doi: 10.1097/HJH.0b013e328312c86a

Fig. 3.

Fig. 3

(a) Changes in systolic blood pressure and renal MBG excretion in Dahl-S rats during 4 weeks of administration of 8% NaCl diet. (b) Plasma levels of MBG in Dahl-S rats during normal NaCl intake (baseline) and following 4 weeks of administration of 8% NaCl diet. (c) Systolic blood pressure and (d) activity of the sodium pump in thoracic aortae in Dahl-S rats at baseline and after 4 weeks of administration of 8% NaCl diet 3 h following intraperitoneal administration of vehicle (VEH), or anti-MBG mAbs, 3E9. Each point or bar represents means ± SEM from 10 observations. By one-way ANOVA followed by Newman–Keuls test: *P < 0.05; **P < 0.01 vs. baseline or time 0; #P < 0.05 vs. VEH. By two-tailed t-test: @P < 0.01 vs. baseline. BL, baseline; MBG, marinobufagenin; SBP, systolic blood pressure.