Systolic blood pressure (a) and activity of the sodium pump in the thoracic aorta (b) in virgin rats, in pregnant rats (day 19 of gestation) without NaCl supplementation (Pr LS) and in NaCl-supplemented pregnant rats (Pr HS) treated with 3E9 anti-MBG mAb or with vehicle (VEH). Means ± SEM from 8–10 observations. By one-way ANOVA followed by Newman–Keuls test: *P < 0.05; **P < 0.01 vs. virgin rats. #P < 0.01 vs. Pr HS, VEH. Pr HS, pregnant rats with high-salt intake; Pr LS, pregnant rats with low-salt intake; mAb, monoclonal anti-marinobufagenin antibody; MBG, marinobufagenin.