Table 1.
Demographic, Cognitive, and Apolipoprotein-E (APOE) ε4 Comparisons by Depression Status and Gender
| AD Groups by Depression Status | AD Groups by Gender | |||||
|---|---|---|---|---|---|---|
| Clinically Depressed(N=61) | Not Depressed (N=262) | p-value* | Women (N=160) | Men (N=163) | p-value | |
| Demographics | ||||||
| Age, mean (SD) | 72.1 (7.0) | 72.7 (9.7) | 0.657 | 72.9 (10.8) | 72.3 (7.5) | 0.586 |
| Female, % | 54.1 | 48.5 | 0.429 | - | - | - |
| Education, mean (SD) | 12.8 (4.1) | 13.2 (4.1) | 0.445 | 12.2 (3.8) | 14.0 (4.2) | <0.001 |
| Clinical Features | ||||||
| Depressed, % | - | - | 20.6 | 17.2 | 0.429 | |
| Years of AD, mean (SD) | 4.3 (2.5) | 3.7 (2.4) | 0.087 | 3.7 (2.3) | 4.0 (2.6) | 0.198 |
| DRS, mean (SD) | 102.1 (25.7) | 103.0 (21.1) | 0.765 | 102.5 (22.0) | 103.2 (22.2) | 0.783 |
| MMSE, mean (SD) | 20.9 (5.7) | 20.3 (5.4) | 0.484 | 20.0 (5.4) | 20.8 (5.6) | 0.185 |
| APOE Status | ||||||
| APOE ε4 Positive, % | 77.0 | 58.0 | 0.042 | 64.4 | 57.1 | 0.178 |