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. Author manuscript; available in PMC: 2009 Oct 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2008 Jul 12;232(2):236–243. doi: 10.1016/j.taap.2008.06.022

Figure 4.

Figure 4

FTICR-MS analysis of liver metabolome identifies molecules affected by alcohol in the mouse. Expansion of the ~40 Da m/z window (from ~280 to ~330 m/z) in FTICR-MS spectra obtained from six high-fat control (A) and six alcohol-treated (B) liver samples. (C) Expansion of the m/z range from 309.22 to 309.32 showing overlaid FTICR-MS spectra from samples depicted in A and B. Four metabolites were found within this 0.10 Da window and 11, 14-eicosadienoic acid (m/z 309.278459) could be identified on the basis of accurate mass and it is elevated in liver after alcohol treatment.