Figure 1.

Mask design of the 16-channel CE chip for parallel DNA sequencing. Sixteen identical 250-μm twin-T injectors are used for all channels. All lines on the mask have a width of 10 μm. A final channel width of ≈110 μm is obtained with a depth of 50 μm. The wafers used have a diameter of 10 cm and a thickness of 1.1 mm. All reservoirs are formed by access holes drilled on the etched wafer. The diameter of the access holes is ca. 1.4 mm for sample and waste and 2.1 mm for cathode and anode, which respectively correspond to ca. 1.7-μl and ca. 3.8-μl volume reservoirs. The alignment holes have a diameter of 2.1 mm. (Inset) Detail of the compensation of different channel lengths.