FIG. 3.
Prevalence of IgM antibodies to recombinant protein MPL21 in sera from individuals diagnosed with leptospirosis as determined by ELISA. (A) Serum samples diluted 1:100 were considered positive when the mean OD492 values were above the mean plus 3 standard deviations for six uninfected control serum samples. *, a significant increase in the frequency of responders containing IgM antibodies in convalescent-phase serum (P < 0.05). (B) The antibody titers of each individual represent the last dilution that had an OD492 greater than 0.1. The horizontal lines represent the geometric mean antibody titers for each group. No statistically significant difference in antibody levels was observed between the two tests.