TABLE 3.
Summary of diagnostic serological responses as determined by different methods for sera of cervids (C. elaphus) experimentally infected with M. bovis
| Test method | Rate (no. of animals with antigen/total no. of animals)a for indicated no. of days p.i.
|
Overall sensitivity (%)b | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 30 | 44 | 58 | 72 | 86 | 114 | 140 | 171 | 192 | 199 | 206 | 213 | ||
| MAPIA | 2/10 | 6/10 | 8/10 | 8/10 | 8/10 | 8/10 | 8/10 | 8/10 | 9/10 | 9/10 | 9/10 | 9/10 | 76.7 |
| Lateral flow | 2/10 | 5/10 | 9/10 | 7/10 | 7/10 | 7/10 | 7/10 | 8/10 | 8/10 | 9/10 | 9/10 | 9/10 | 72.5 |
| FPA | 0/10 | 0/10 | 0/10 | 0/10 | 3/10 | 4/10 | 6/10 | 5/10 | 6/10 | 6/10 | 5/10 | 5/10 | 33.3 |
a
Values indicate rates of antigen recognition among infected animals as measured at various time points p.i. Tuberculin skin testing was performed at 184 days p.i.
b
A composite diagnostic sensitivity based on all time points sampled over the infection study.