FIG. 4.

Multiple subfamilies of adhesin-like proteins exist in C. glabrata. A neighbor-joining phylogenetic tree, with bootstrap values added (1,000 bootstraps performed), of adhesin-like wall proteins based on the putative functional domains (the 300 N-terminal amino acids or fewer in cases where the N-terminal ORF fragment is shorter) of the ORFs is shown. S/T-rich low-complexity regions within the first 300 amino acids of CAGL0C00209g and CAGL0G10175 were excluded from this analysis. CAGL0L09911g, which together with CAGL0J05170g is least related to other adhesin-like proteins, is plotted as an outgroup. The distantly related S. cerevisiae Flo1 and Dan1 and C. albicans Hyr1 are included for comparison. CAGL0H00110g (group VII) and CAGL0E00187g (group IV) were excluded from this analysis since their N-terminal parts are unidentified; see Fig. 3. The scale bar indicates phylogenetic distances, in number of amino acid substitutions per position.