FIG. 2.

Time course of temperature data in B. anthracis aerosol-exposed AGMs and illustration of time points positive for clinical assays. (a) Survivor; (b) AGM with low-grade fever 24 h after becoming bacteremic and antigenemic; (c) AGM with fever spike preceding bacteremia and antigenemia; (d) AGM with absence of fever in the presence of bacteremia and antigenemia. B, bacteremia (the first time point at which B. anthracis was detected in blood by culture); E, antigenemia (the first time point at which the PA was detected in blood by the ECL assay); P, antigenemia (the first time point in which both PA and capsule markers were detected in blood by the PCR assay).