TABLE 4.

Example of ECL data from AGMs aerosol exposed to high doses of B. anthracis^a

Monkey	Dose, CFU/ml of blood (LD50)	Time		Bacteremia (CFU/ml)	ECL data for:
		Day	Hour		PA		Capsule
					S/N value	Concn (ng/ml)	S/N value	Concn (ng/ml)
V537	1.6E + 07 (1,455)	−2	−48	0	0.99	BLD	1.08	BLD
		0	7	0	0.98	BLD	NT	BLD
		1	24	0	1.00	BLD	1.17	BLD
			36	0	1.15	BLD	1.17	BLD
		2	48	940	67.76	54	43.19	>1,000
			60	NT	NT	NT	NT	NT
		3	72	>1,000	NT	NT	NT	NT
			84	NT	NT	NT	NT	NT
W164	1.9E + 07 (1,727)	−2	−48	0	0.96	BLD	0.90	BLD
		0	7	0	0.97	BLD	NT	NT
		1	24	0	0.96	BLD	0.95	BLD
			36	0	1.04	BLD	NT	NT
		2	48	>1,000	11.39	8	9.24	312
			60	900	50.75	40	26.96	>1,000
		3	72	>1,000	68.43	55	20.43	>1,000
			84	>1,000	70.54	57	1.19	Prozone
V540	1.1E + 07 (1,000)	−2	−48	0	1.09	BLD	1.10	BLD
		0	7	0	1.00	BLD	NT	NT
		1	24	0	1.04	BLD	NT	NT
			36	0	1.04	BLD	NT	NT
		2	48	0	1.11	BLD	1.05	BLD
			60	0	1.12	BLD	NT	NT
		3	72	0	1.27	BLQ	1.08	BLD
			84	260	2.92	1	2.48	88
		4	96	>1,000	223.83	202	1.82	>1,000
		5	120	NT	NT	NT	NT	NT
V547	1.3E + 07 (1,182)	−2	−48	0	0.98	BLD	0.92	BLD
		0	7	0	0.99	BLD	NT	NT
		1	24	0	0.99	BLD	NT	NT
			36	0	1.01	BLD	NT	NT
		2	48	0	1.02	BLD	0.87	BLD
			60	NT	NT	NT	NT	NT
		3	72	0	1.18	BLD	0.93	BLD
			84	60	3.62	2	4.23	114
		4	96	820	25.62	40	15.24	>1,000
		5	120	10	NT	NT	NT	NT
		6	144	144	NT	NT	NT	NT

^aValues in boldface are positive. BLD, below the LOD; NT, not tested; BLQ, below the limit of quantitation.