TABLE 4.
Cytokine response of splenocytes from C.B-17-WT and C.B-17-SCID mice at day 10 postinfection
| Mouse | Treatment | IFN-γ (pg/ml)
|
||
|---|---|---|---|---|
| EBa | ConAb | Medium | ||
| C.B-17-WT | MoPn-23 | 17,663 ± 1,590*† | 18,722 ± 1,987 | <0.03 |
| C.B-17-SCID | MoPn-23 | 675 ± 15 | 52 ± 110 | <0.03 |
| C.B-17-WT | NL-IgG | 17,476 ± 760*† | 15,907 ± 158 | <0.03 |
| C.B-17-SCID | NL-IgG | 766 ± 180 | <0.03 | <0.03 |
a
UV-inactivated C. trachomatis MoPn EB were added at a 10:1 ratio to the antigen-presenting cells. *, P < 0.05 as determined by the Student t test compared to the C.B-17-SCID mice receiving MoPn MAb 23; †, P < 0.05 as determined by the Student t test compared to the C.B-17-SCID mice receiving NL-IgG.
b
ConA was added at a concentration of 5 μg/ml.