FIG. 3.

Levels of B. burgdorferi (Bb) in tissues from control C3H (wild-type) and C3H IL-10^−/− (IL-10 ko) mice 21 days after infection with B. burgdorferi. B. burgdorferi DNA copy numbers in the ankle joint (A) or in ear tissue (B) were determined using real-time PCR and normalized using the single-copy mouse gene nidogen. The bars represent pooled means from two separate experiments; n = 10. An asterisk indicates that the IL-10 ko value is significantly different from the wt value at the P < 0.001 level. fla, flagellin.