FIG. 6.

Development of arthritis and levels of B. burgdorferi in ankle tissue and Borrelia-specific IgG antibodies in C3H mice treated with adenoviral vectors. The mice were treated as described in the legend to Fig. 5. The mice were sacrificed on day 14 postinfection, and the increases in ankle diameters (A) and severity scores (B), as well as levels of B. burgdorferi in ankle joint tissue (C) and Borrelia-specific IgG levels in sera (D), were determined as described in Materials and Methods. The data are means plus standard errors and are representative of two separate experiments with similar results. n = 5 per group.