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. 2008 Sep 24;82(23):11749–11757. doi: 10.1128/JVI.01128-08

FIG. 4.

FIG. 4.

The average number of target cells killed per day by one epitope-specific effector or one memory CD8 T cell. The number of target cells killed per day is simply KT(t)/E, where T(t) is the number of target cells taken from the data, K is the death rate of pulsed targets, and E is the average number of epitope-specific CD8 T cells in the spleen (see Table 1). Note that by calculating the average number of targets killed per day by one CD8 T cell, we do not make any assumptions on the type of the killing term. Also note that the number of targets killed per day per CD8 T cell is not the per-capita killing efficacy of CD8 T cells, as it was estimated in previous studies (37, 51). The average number of target cells killed per day by an NP396-specific effector or memory CD8 T cell is 0.7 or 5.4, respectively, and that for a GP276-specific effector or memory CD8 T cell is 1.2 or 4.2 cells per day, respectively.